Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780373 | 0.88 | HCAR2 (0.59) | PLA2G4BHCAR2TP53TSHR | |
| SCHEMBL12704019 | 0.75 | MAPT (0.52) | SMN1; SMN2KDM4EHCAR2ALDH1A1TP53 | |
| SCHEMBL4517538 | 0.73 | MAPK1 (0.53) | ALPLPLA2G2AHCAR2ALDH1A1NPC1 | |
| SCHEMBL13523553 | 0.72 | KDM4E (0.47) | ALPLPLA2G2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL3052051 | 0.72 | MAPT (0.74) | PLA2G4BSMN1; SMN2CYP1A2CYP2D6TP53 | |
| SCHEMBL7171003 | 0.72 | MAPT (0.74) | PLA2G4BSMN1; SMN2CYP1A2CYP2D6TP53 | |
| SCHEMBL302596 | 0.72 | MAPT (0.74) | PLA2G4BSMN1; SMN2CYP1A2CYP2D6TP53 | |
| SCHEMBL3051371 | 0.72 | MAPT (0.74) | PLA2G4BSMN1; SMN2CYP1A2CYP2D6TP53 | |
| SCHEMBL21908583 | 0.72 | MAPT (0.74) | PLA2G4BSMN1; SMN2CYP1A2CYP2D6TP53 | |
| SCHEMBL12113908 | 0.72 | MAPT (0.74) | PLA2G4BSMN1; SMN2CYP1A2CYP2D6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |