Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119849 | 0.87 | UBE2N (0.49) | UBE2NEPHX1ALDH1A1MEN1MAPT | |
| SCHEMBL8780446 | 0.83 | UBE2N (0.50) | UBE2NLTB4R2EPHX1CHRM1HSD17B10 | |
| SCHEMBL4801536 | 0.82 | UBE2N (0.56) | UBE2NEPHX1CHRM1 | |
| SCHEMBL4805977 | 0.80 | UBE2N (0.53) | UBE2NEPHX1ALDH1A1CHRM1 | |
| SCHEMBL4804049 | 0.80 | UBE2N (0.53) | UBE2NEPHX1ALDH1A1CHRM1 | |
| SCHEMBL4799006 | 0.80 | UBE2N (0.59) | UBE2NEPHX1CHRM1 | |
| SCHEMBL1296553 | 0.79 | EPHX1 (0.56) | UBE2NEPHX1ADRB1ADRB3ALDH1A1 | |
| SCHEMBL3632556 | 0.79 | LMNA (0.50) | UBE2NALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL4800161 | 0.78 | UBE2N (0.57) | UBE2NEPHX1CHRM1 | |
| SCHEMBL9577453 | 0.76 | EPHX1 (0.53) | UBE2NEPHX1ADRB1ADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498722-B1 | Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1997-07-30 | — | — | EP | disclosed |
| US-5478938-A | Antagonists for angiotensin II receptors; hypotensive, cardiotonic agents; cognitive activators | ROUSSEL UCLAF (FR) | 1995-12-26 | — | — | US | disclosed |
| WO-1995026206-A1 | METHOD FOR PREPARING RADIONUCLIDE-LABELED CHELATING AGENT-LIGAND COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-10-05 | — | — | WO | disclosed |
| US-5324839-A | Hypotensive agents, gastrointestinal and urogenital disorders | ROUSSEL-UCLAF (FR) | 1994-06-28 | — | — | US | disclosed |
| EP-0498722-A1 | Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |