Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 6/20 | 0.63 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 6/20 | 0.63 |
| ▸ | SI | P14410 | 6/20 | 0.63 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | F12 | P00748 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780382 | 0.87 | MGAM (0.66) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8780422 | 0.87 | MGAM (0.66) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27482235 | 0.83 | MGAM (0.76) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27481100 | 0.82 | MGAM (0.93) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL7340170 | 0.81 | MAPT (0.53) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8780395 | 0.80 | MGAM (0.73) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL6134508 | 0.80 | MGAM (0.80) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL7333590 | 0.79 | MAPT (0.67) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL8780380 | 0.78 | GAA (0.62) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27481488 | 0.76 | MGAM (0.67) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |