Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443950 | 0.80 | TSHR (0.35) | HDAC8 | |
| SCHEMBL11312017 | 0.77 | GRM5 (0.32) | — | |
| SCHEMBL25337982 | 0.77 | NPC1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL11317533 | 0.76 | GRM5 (0.31) | — | |
| SCHEMBL8485997 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL13262247 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL18265853 | 0.69 | HDAC8 (0.35) | HDAC8 | |
| SCHEMBL20964349 | 0.67 | — | — | |
| SCHEMBL21936377 | 0.67 | POLB (0.38) | — | |
| SCHEMBL28159746 | 0.67 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679684-A | INTIINFLAMMATORY AGENTS, ANTIARTHRITIS AGENTS, NERVOUS SYSTEM DISORDERS, AIDS | MACRONEX, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0766691-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035304-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1995-12-28 | — | — | WO | disclosed |