Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215267 | 0.73 | HIF1A (0.34) | MDM2KMT2AGRIN2BHIF1AEPAS1 | |
| SCHEMBL14127766 | 0.72 | GRIN2B (0.36) | KMT2AGRIN2BLMNA | |
| SCHEMBL5798396 | 0.72 | — | — | |
| SCHEMBL5983969 | 0.71 | HTT (0.34) | — | |
| SCHEMBL27844267 | 0.71 | CES2 (0.32) | HIF1AEPAS1CES2LMNACES1 | |
| SCHEMBL6883876 | 0.71 | — | — | |
| SCHEMBL379830 | 0.71 | CES2 (0.32) | HIF1AEPAS1CES2LMNACES1 | |
| SCHEMBL9192197 | 0.71 | — | — | |
| SCHEMBL6891299 | 0.71 | — | — | |
| SCHEMBL4627136 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775151-A2 | SIALIC ACID/FUCOSE BASED MEDICAMENTS | GLYCOMED INCORPORATED (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005209-A9 | SIALIC ACID/FUCOSE BASED MEDICAMENTS | — | 1996-04-11 | — | — | WO | disclosed |
| WO-1996005209-A2 | SIALIC ACID/FUCOSE BASED MEDICAMENTS | GLYCOMED, INCORPORATED (US) | 1996-02-22 | — | — | WO | disclosed |