Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780944 | 0.77 | TAAR1 (0.60) | TAAR1SMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL13913066 | 0.70 | HRH4 (0.49) | MAOBMAOAHRH4HRH3NPC1 | |
| SCHEMBL4069939 | 0.70 | TDP1 (0.64) | HRH4HRH3L3MBTL1TDP1MEN1 | |
| SCHEMBL3524253 | 0.69 | HRH3 (0.44) | MAOBMAOAHRH4HRH3ALDH1A1 | |
| SCHEMBL3524697 | 0.68 | ADORA1 (0.43) | SMN1; SMN2MAOBMAOAHRH4HRH3 | |
| SCHEMBL2640223 | 0.68 | TSHR (0.70) | HRH4HRH3L3MBTL1TDP1 | |
| SCHEMBL8621469 | 0.68 | TSHR (0.70) | HRH4HRH3L3MBTL1TDP1 | |
| SCHEMBL3438748 | 0.67 | TDP1 (0.60) | HRH4HRH3L3MBTL1TDP1MEN1 | |
| SCHEMBL13133688 | 0.67 | HRH4 (0.45) | SMN1; SMN2MAOBMAOAHRH4HRH3 | |
| SCHEMBL9011595 | 0.66 | TSHR (0.67) | SMN1; SMN2HRH4HRH3L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |