Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771886 | 0.79 | HSD11B1 (0.36) | HSD11B1CYP2C9CYP3A4 | |
| SCHEMBL9005074 | 0.79 | HSD11B1 (0.38) | HSD11B1CYP2C9CYP3A4BACE1HCAR2 | |
| SCHEMBL3454385 | 0.79 | HSD11B1 (0.36) | HSD11B1CYP2C9CYP3A4 | |
| SCHEMBL8723263 | 0.79 | HSD11B1 (0.38) | HSD11B1CYP2C9CYP3A4BACE1HCAR2 | |
| SCHEMBL18754946 | 0.74 | PDE2A (0.37) | — | |
| SCHEMBL2874324 | 0.73 | HSD11B1 (0.37) | HSD11B1CYP2C9OPRM1OPRL1 | |
| SCHEMBL28721499 | 0.72 | KMT2A (0.36) | ALDH1A1HPGD | |
| SCHEMBL23612354 | 0.69 | HDAC4 (0.37) | HDAC4BACE1OPRM1OPRD1OPRK1 | |
| SCHEMBL15705147 | 0.68 | BACE1 (0.33) | HDAC4BACE1HCAR2 | |
| SCHEMBL17673207 | 0.67 | BACE1 (0.40) | HDAC4BACE1HCAR2BACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809640-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025410-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-22 | — | — | WO | disclosed |