Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18763131 | 0.84 | TDP1 (0.64) | TDP1ESR2ESR1RAB9AMAPK1 | |
| SCHEMBL8349234 | 0.84 | TDP1 (0.64) | TDP1ESR2ESR1RAB9AMAPK1 | |
| SCHEMBL29173159 | 0.84 | TDP1 (0.64) | TDP1ESR2ESR1RAB9AMAPK1 | |
| SCHEMBL579010 | 0.84 | TDP1 (0.64) | TDP1ESR2ESR1RAB9AMAPK1 | |
| SCHEMBL11675019 | 0.83 | LMNA (0.53) | TDP1ESR1RAB9AC5AR1SMN1; SMN2 | |
| SCHEMBL1278659 | 0.83 | TDP1 (0.67) | TDP1ESR2ESR1RAB9AMAPK1 | |
| SCHEMBL3130566 | 0.83 | TDP1 (0.62) | TDP1ESR2ESR1RAB9AMAPK1 | |
| SCHEMBL4262910 | 0.82 | ESR1 (0.53) | TDP1ESR1RAB9AC5AR1SMN1; SMN2 | |
| SCHEMBL6714372 | 0.81 | TDP1 (0.60) | TDP1ESR2ESR1MAPK1NR1I2 | |
| SCHEMBL2057475 | 0.81 | TDP1 (0.73) | TDP1ESR2ESR1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790985-A1 | N-ACYL-N-ALKYLAMINO PHENYL SULPHONYL UREAS WITH SULPHUR SUBSTITUENTS, PROCESS FOR THEIR PRODUCTION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014304-A1 | N-ACYL-N-ALKYLAMINO PHENYL SULPHONYL UREAS WITH SULPHUR SUBSTITUENTS, PROCESS FOR THEIR PRODUCTION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1996-05-17 | — | — | WO | disclosed |