Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23050191 | 0.88 | GAA (0.38) | TLR8TSHRMAPTHTTMEN1 | |
| SCHEMBL11347930 | 0.82 | TYR (0.47) | TYRTLR8SKP2TSHRMAPT | |
| SCHEMBL5377652 | 0.80 | TYR (0.46) | TYRTLR8SKP2TSHRMAPT | |
| SCHEMBL10492538 | 0.80 | TYR (0.46) | TYRTLR8SKP2TSHRMAPT | |
| SCHEMBL8781072 | 0.79 | GAA (0.41) | TSHRMAPTHTTMEN1TP53 | |
| SCHEMBL13264102 | 0.78 | SKP2 (0.47) | TYRTLR8SKP2TSHRMAPT | |
| SCHEMBL25144469 | 0.78 | TYR (0.44) | TYRTLR8SKP2TSHRMAPT | |
| SCHEMBL22271585 | 0.78 | TYR (0.44) | TYRTLR8SKP2TSHRMAPT | |
| SCHEMBL23864412 | 0.78 | TYR (0.44) | TYRTLR8SKP2TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11214753 | 0.78 | MAPT (0.46) | TYRTLR8SKP2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589952-B1 | USE OF SUPLHUR METAAMINOPHENOLS FOR DYEING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS | OREAL (FR) | 1997-08-27 | — | — | EP | claimed |
| US-5478359-A | Applying a hair dyes | L'OREAL (FR) | 1995-12-26 | — | — | US | disclosed |