Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9995320 | 0.88 | SLC6A4 (0.52) | SLC6A4HTR2ASLC6A2SLC6A3SLC1A5 | |
| SCHEMBL872624 | 0.85 | SLC6A4 (0.53) | SLC6A4HTR2ASLC6A2SLC6A3SLC1A5 | |
| SCHEMBL8471261 | 0.80 | SLC6A4 (0.58) | SLC6A4HTR2ASLC6A2SLC6A3SLC1A5 | |
| SCHEMBL12361548 | 0.79 | SLC6A4 (0.54) | SLC6A4HTR2ASLC6A2SLC6A3SLC1A5 | |
| SCHEMBL13474499 | 0.76 | SLC6A4 (0.53) | SLC6A4HTR2ASLC6A2SLC6A3SLC1A5 | |
| SCHEMBL11648424 | 0.76 | SMN1; SMN2 (0.45) | SLC6A4SLC6A2PPARAMEN1KMT2A | |
| SCHEMBL12353135 | 0.75 | SLC6A4 (0.50) | SLC6A4HTR2ASLC6A2SLC6A3SLC1A5 | |
| SCHEMBL14636285 | 0.75 | NPSR1 (0.44) | SLC6A4SLC6A2SLC6A3POLBCHRM1 | |
| SCHEMBL1146416 | 0.75 | HTR2A (0.54) | SLC6A4HTR2ASLC6A2SLC6A3SLC1A5 | |
| SCHEMBL28801696 | 0.73 | PPARA (0.54) | SLC6A4HTR2ASLC6A2SLC6A3SLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038975-A2 | PROCESS FOR THE PREPARATION OF (3ARS,12BRS)-5-CHLORO-2-METHYL-2,3,3A12B-TETRAHYDRO-1HDIBENZO[2,3:6,7] OXEPINO [4,5-C]PYRROLE MALEATE AND IT'S PHARMACEUTICAL COMPOSITION THEREOF | MSN LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| WO-2012038975-A2 | PROCESS FOR THE PREPARATION OF (3ARS,12BRS)-5-CHLORO-2-METHYL-2,3,3A12B-TETRAHYDRO-1HDIBENZO[2,3:6,7] OXEPINO [4,5-C]PYRROLE MALEATE AND IT'S PHARMACEUTICAL COMPOSITION THEREOF | MSN LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |