Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10093029 | 0.90 | L3MBTL1 (0.44) | NPSR1L3MBTL1GAAMAPTALDH1A1 | |
| SCHEMBL9995320 | 0.86 | SLC6A4 (0.52) | MAPTCHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13752339 | 0.83 | L3MBTL1 (0.43) | NPSR1L3MBTL1GAAMAPTALDH1A1 | |
| SCHEMBL967886 | 0.77 | L3MBTL1 (0.51) | NPSR1L3MBTL1MAPTALDH1A1CHRM1 | |
| SCHEMBL9995153 | 0.77 | PPARG (0.40) | NPSR1L3MBTL1GAAMAPTALDH1A1 | |
| SCHEMBL7400584 | 0.76 | CHRM1 (0.65) | NPSR1L3MBTL1MAPTCHRM1SLC6A4 | |
| SCHEMBL872624 | 0.76 | SLC6A4 (0.53) | L3MBTL1MAPTALDH1A1CHRM1SLC6A2 | |
| SCHEMBL878121 | 0.75 | SLC6A4 (0.47) | MAPTCHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12929644 | 0.75 | CYP1A2 (0.57) | MAPTCHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8471261 | 0.72 | SLC6A4 (0.58) | MAPTCHRM1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145421-B2 | Process for the preparation of asenapine maleate | RANBAXY LABORATORIES LIMITED (IN) | 2015-09-29 | — | — | US | disclosed |
| US-20150112083-A1 | PROCESS FOR THE PREPARATION OF ASENAPINE MALEATE | RANBAXY LABORATORIES LIMITED (IN) | 2015-04-23 | — | — | US | disclosed |
| WO-2013011461-A1 | PROCESS FOR THE PREPARATION OF ASENAPINE MALEATE | RANBAXY LABORATORIES LIMITED (IN) | 2013-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150112083-A1 | PROCESS FOR THE PREPARATION OF ASENAPINE MALEATE | DHPS, SCN5A, CYP3A5 | NPSR1 818/4885L3MBTL1 4817/4885GAA 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.