Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21162187 | 0.98 | OPRM1 (0.43) | OPRM1SHBGSPHK1CYP1A2SIGMAR1 | |
| SCHEMBL9211350 | 0.98 | OPRM1 (0.43) | OPRM1SPHK1CYP1A2TP53LAP3 | |
| SCHEMBL9209599 | 0.98 | OPRM1 (0.43) | OPRM1SPHK1CYP1A2TP53LAP3 | |
| SCHEMBL9204894 | 0.98 | OPRM1 (0.43) | OPRM1SPHK1CYP1A2TP53LAP3 | |
| SCHEMBL11296526 | 0.96 | OPRM1 (0.41) | OPRM1SHBGSPHK1CYP1A2SIGMAR1 | |
| SCHEMBL11576178 | 0.96 | OPRM1 (0.41) | OPRM1SHBGSPHK1CYP1A2SIGMAR1 | |
| SCHEMBL9213543 | 0.96 | OPRM1 (0.41) | OPRM1SHBGSPHK1CYP1A2SIGMAR1 | |
| SCHEMBL9211126 | 0.96 | OPRM1 (0.41) | OPRM1SHBGSPHK1CYP1A2SIGMAR1 | |
| SCHEMBL9208863 | 0.96 | OPRM1 (0.41) | OPRM1SHBGSPHK1CYP1A2SIGMAR1 | |
| SCHEMBL10435741 | 0.96 | OPRM1 (0.41) | OPRM1SHBGSPHK1CYP1A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643685-B1 | PALLADIUM CATALYZED ADDITION OF AMINES TO 3,4-EPOXY-1-BUTENE | EASTMAN CHEM CO (US) | 1997-01-22 | — | — | EP | disclosed |
| EP-0643685-A1 | PALLADIUM CATALYZED ADDITION OF AMINES TO 3,4-EPOXY-1-BUTENE. | EASTMAN CHEM CO (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5326873-A | Catalyst selectivity | EASTMAN KODAK COMPANY (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1993025516-A1 | PALLADIUM CATALYZED ADDITION OF AMINES TO 3,4-EPOXY-1-BUTENE | EASTMAN CHEMICAL COMPANY (US) | 1993-12-23 | — | — | WO | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |