Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782188 | 0.86 | KMT2A (0.45) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8782447 | 0.82 | NPC1 (0.52) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8783200 | 0.81 | LCK (0.50) | KMT2AKDM4EL3MBTL1ESR1ESR2 | |
| SCHEMBL10433074 | 0.80 | ESR1 (0.66) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8782528 | 0.79 | AR (0.38) | KMT2AKDM4EL3MBTL1ESR1ESR2 | |
| SCHEMBL8782709 | 0.76 | NPC1 (0.50) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8782389 | 0.73 | CA1 (0.41) | KMT2AKDM4ENPC1RAB9AHDAC1 | |
| SCHEMBL8782104 | 0.71 | MEN1 (0.39) | KMT2AMEN1SMN1; SMN2ALDH1A1HDAC1 | |
| SCHEMBL10432810 | 0.71 | MEN1 (0.62) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8783453 | 0.70 | NPC1 (0.47) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556720-B1 | 5-Aminoflavone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5539112-A | 5-aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0556720-A1 | 5-Aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |