Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.50 |
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783323 | 0.84 | LCK (0.51) | LCKARPRKDCEGFRSRC | |
| SCHEMBL8782616 | 0.82 | LCK (0.50) | LCKARPRKDCEGFRSRC | |
| SCHEMBL8783205 | 0.82 | LCK (0.50) | LCKARPRKDCEGFRSRC | |
| SCHEMBL10432565 | 0.82 | LCK (0.63) | LCKARPRKDCEGFRSRC | |
| SCHEMBL8782528 | 0.81 | AR (0.38) | LCKARPRKDCESR1ESR2 | |
| SCHEMBL8782155 | 0.81 | KMT2A (0.45) | ARESR1ESR2CYP1B1KDM4E | |
| SCHEMBL10432914 | 0.79 | TERT (0.54) | CYP1B1KDM4EPOLBGAAMAPT | |
| SCHEMBL8782890 | 0.78 | LCK (0.62) | LCKAREGFRSRCESR1 | |
| SCHEMBL1559529 | 0.74 | CYP1B1 (0.54) | LCKAREGFRSRCESR1 | |
| SCHEMBL1560703 | 0.74 | ESR1 (0.78) | LCKAREGFRSRCESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556720-B1 | 5-Aminoflavone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5539112-A | 5-aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0556720-A1 | 5-Aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |