Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782814 | 1.00 | HTR2C (0.47) | HTR2CHTR2AHTR2BALDH1A1KDM4E | |
| SCHEMBL8782808 | 1.00 | HTR2C (0.47) | HTR2CHTR2AHTR2BALDH1A1KDM4E | |
| SCHEMBL8783174 | 0.83 | HTR2C (0.39) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL8783180 | 0.83 | HTR2C (0.39) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL316868 | 0.79 | HTR2C (0.48) | HTR2CHTR2AHTR2BALDH1A1KDM4E | |
| SCHEMBL10108958 | 0.79 | HTR2C (0.48) | HTR2CHTR2AHTR2BALDH1A1KDM4E | |
| SCHEMBL8783014 | 0.72 | MEN1 (0.52) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL8783020 | 0.72 | MEN1 (0.52) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL8783012 | 0.72 | MEN1 (0.52) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL25044117 | 0.70 | HTR2C (0.68) | HTR2CHTR2AHTR2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556119-B1 | Pyrrolidine derivatives substituted in the 3-position with a saturated or insaturated fatty acid group, process for their preparation and pharmaceuticals with thromboxane A2 inhibiting activity containing them | ADIR (FR) | 1997-05-14 | — | — | EP | disclosed |
| US-5407946-A | Pyrrolidine compounds which are useful as thromboxane AZ-inhibitors | ADIR ET COMPAGNIE (FR) | 1995-04-18 | — | — | US | disclosed |
| US-5387591-A | Possesses antithromboxane A2 properties; useful in treatment and prevention of thrombotic diseases | ADIR ET COMPAGNIE (FR) | 1995-02-07 | — | — | US | disclosed |
| EP-0556119-A1 | Novel pyrrolidine derivatives substituted in the 3-position with a saturated or insaturated fatty acid group, process for their preparation and pharmaceuticals with thromboxane A2 inhibiting activity containing them | ADIR ET COMPAGNIE (FR) | 1993-08-18 | — | — | EP | disclosed |