Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541925 | 0.80 | MAPT (0.41) | GAAKDM4EMAPK1MAPTKMT2A | |
| SCHEMBL4644681 | 0.78 | GAA (0.50) | GAAKDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL2760999 | 0.78 | HPGD (0.46) | GAAKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL7136988 | 0.77 | KDM4E (0.50) | GAAKDM4EMAPK1MAPTKMT2A | |
| SCHEMBL11042130 | 0.77 | KMT2A (0.39) | GAAKDM4EMAPK1MAPTKMT2A | |
| SCHEMBL6691255 | 0.77 | TOP2A (0.45) | KDM4EMAPK1MAPTKMT2AMEN1 | |
| SCHEMBL6346568 | 0.77 | KDM4E (0.47) | GAAKDM4EMAPK1MAPTKMT2A | |
| SCHEMBL7135919 | 0.77 | KMT2A (0.48) | GAAKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL11467623 | 0.75 | KMT2A (0.56) | KDM4EMAPTKMT2AMEN1NCOA1 | |
| SCHEMBL27499512 | 0.75 | HPGD (0.43) | GAAKDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560898-B1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES INC (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5340857-A | Ophthalmic lenses, plastic transparencies | PPG INDUSTRIES, INC. (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0560898-A4 | PHOTOCHROMIC NAPHTHOPYRANS | — | 1993-11-18 | — | — | EP | disclosed |
| EP-0560898-A1 | PHOTOCHROMIC NAPHTHOPYRANS. | PPG INDUSTRIES INC (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5244602-A | Photochromic articles comprising polymerized organic host material and naphthopyran | PPG INDUSTRIES, INC. (US) | 1993-09-14 | — | — | US | disclosed |
| WO-1992009593-A1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1992-06-11 | — | — | WO | disclosed |