SCHEMBL6541925

SCHEMBL6541925

O=C(Cl)Oc1cc2ccccc2cc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.41
KMT2A Q03164 4/20 0.41
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
GAA P10253 2/20 0.41
HPGD P15428 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MITF O75030 1/20 0.41
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
POLB P06746 1/20 0.40
NCEH1 Q6PIU2 1/20 0.40
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TTR P02766 1/20 0.39
SERPINE1 P05121 1/20 0.38
NPC1 O15118 1/20 0.38
MAPK1 P28482 1/20 0.38
NOD2 Q9HC29 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11042130 0.96 KMT2A (0.39) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL2760999 0.82 HPGD (0.46) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL7135919 0.81 KMT2A (0.48) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL6346568 0.81 KDM4E (0.47) MAPTKMT2AKDM4ETDP1GAA
SCHEMBL8782843 0.80 GAA (0.41) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL7258349 0.79 ALDH1A1 (0.56) KMT2AKDM4EMEN1HPGDALDH1A1
SCHEMBL27499512 0.79 HPGD (0.43) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL7136988 0.78 KDM4E (0.50) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL8782746 0.78 KMT2A (0.59) MAPTKMT2AKDM4EMEN1TDP1
SCHEMBL1801152 0.77 ELANE (0.49) MAPTKMT2AKDM4EMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1167460-B1 Process for the preparation of disazo condensation pigments in microreactors CLARIANT FINANCE BVI LTD (VG) 2004-05-06 EP disclosed
EP-1167460-A1 Process for the preparation of disazo condensation pigments in microreactors CLARIANT INTERNATIONAL LTD. (CH) 2002-01-02 EP disclosed
EP-0241419-B1 PIGMENTS CONTAINING PIPERIDYL GROUPS SANDOZ AG (CH) 1993-05-19 EP disclosed
EP-0241419-A2 Pigments containing piperidyl groups SANDOZ AG (CH) 1987-10-14 EP disclosed