Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784871 | 0.96 | EDNRA (0.48) | EDNRASLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL8784052 | 0.92 | EDNRA (0.44) | EDNRASLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL8784103 | 0.85 | SLC22A12 (0.41) | EDNRASLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL7496900 | 0.81 | EDNRA (0.64) | EDNRASLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL8784040 | 0.80 | SLC22A12 (0.41) | EDNRASLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL8046639 | 0.80 | EDNRA (0.65) | EDNRASLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL7506376 | 0.79 | EDNRA (0.51) | EDNRASLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL8592901 | 0.78 | EDNRA (0.70) | EDNRASLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL7496869 | 0.77 | EDNRA (0.66) | EDNRASLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL8043446 | 0.77 | EDNRA (0.59) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776325-A1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1997-06-04 | — | — | EP | disclosed |