Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.97 |
| ▸ | MEN1 | O00255 | 1/20 | 0.97 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558887 | 0.98 | MEN1 (1.00) | KMT2ATDP1MEN1TP53TSHR | |
| SCHEMBL13193431 | 0.98 | MEN1 (1.00) | KMT2ATDP1MEN1TP53TSHR | |
| Tofa SCHEMBL543676 | 0.98 | MEN1 (1.00) | KMT2ATDP1MEN1TP53TSHR | |
| SCHEMBL11561346 | 0.98 | MEN1 (1.00) | KMT2ATDP1MEN1TP53TSHR | |
| SCHEMBL992112 | 0.98 | MEN1 (1.00) | KMT2ATDP1MEN1TP53TSHR | |
| SCHEMBL9060429 | 0.98 | MEN1 (1.00) | KMT2ATDP1MEN1TP53TSHR | |
| Tofa SCHEMBL11555343 | 0.97 | MEN1 (0.97) | KMT2ATDP1MEN1TP53TSHR | |
| SCHEMBL10669926 | 0.90 | TDP1 (0.84) | KMT2ATDP1MEN1TP53TSHR | |
| SCHEMBL10669914 | 0.90 | TDP1 (0.84) | KMT2ATDP1MEN1TP53TSHR | |
| SCHEMBL10669917 | 0.90 | TDP1 (0.84) | KMT2ATDP1MEN1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417651-A | A kind of method for preparing 2,5 furandicarboxylic acids and its derivative | 合肥利夫生物科技有限公司 | 2017-12-01 | — | — | CN | disclosed |
| EP-0595995-B1 | ARYLAMIDOALKYL- AND ARYLAMINOALKYL-N-HYDROXYUREA COMPOUNDS AND -N-HYDROXYFORMAMIDE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0595995-A4 | ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0595995-A1 | ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY. | ABBOTT LAB (US) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993002037-A1 | ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1993-02-04 | — | — | WO | disclosed |