Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 12/20 | 0.55 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785109 | 0.91 | TACR1 (0.61) | KCNA5KCNH2TACR1F2RL3DPP4 | |
| SCHEMBL8785635 | 0.85 | TACR1 (0.61) | KCNA5KCNH2TACR1F2RL3DPP4 | |
| SCHEMBL3115349 | 0.84 | KCNA5 (0.76) | KCNA5KCNH2TACR1F2RL3DPP4 | |
| SCHEMBL8785202 | 0.83 | TACR1 (0.72) | KCNA5KCNH2TACR1F2RL3DPP4 | |
| SCHEMBL1379988 | 0.82 | KCNA5 (0.64) | KCNA5KCNH2TACR1F2RL3DPP4 | |
| Hydrochloric Acid SCHEMBL3112400 | 0.81 | KCNA5 (0.62) | KCNA5KCNH2TACR1F2RL3DPP4 | |
| SCHEMBL8785655 | 0.80 | TACR1 (0.56) | KCNA5KCNH2TACR1KDM4ESMN1; SMN2 | |
| SCHEMBL8785588 | 0.78 | TACR1 (0.68) | KCNA5KCNH2TACR1F2RL3DPP4 | |
| SCHEMBL1382996 | 0.77 | KCNA5 (0.76) | KCNA5KCNH2TACR1F2RL3DPP4 | |
| SCHEMBL8786372 | 0.77 | TACR1 (0.51) | KCNA5KCNH2TACR1F2RL3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |