Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.51 |
| ▸ | DPP4 | P27487 | 3/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785635 | 0.91 | TACR1 (0.61) | TACR1DPP4KCNA5KCNH2F2RL3 | |
| SCHEMBL8785109 | 0.82 | TACR1 (0.61) | TACR1DPP4KCNA5KCNH2F2RL3 | |
| SCHEMBL8835008 | 0.80 | TACR1 (0.51) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8785449 | 0.80 | TACR1 (0.75) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8835015 | 0.79 | TACR1 (0.50) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8785588 | 0.79 | TACR1 (0.68) | TACR1DPP4KCNA5KCNH2F2RL3 | |
| SCHEMBL8947993 | 0.78 | DPP4 (0.71) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8785566 | 0.78 | TACR1 (0.56) | TACR1DPP4KCNA5KCNH2 | |
| SCHEMBL8784402 | 0.77 | KCNA5 (0.55) | TACR1DPP4KCNA5KCNH2F2RL3 | |
| SCHEMBL8948096 | 0.76 | TACR1 (0.54) | TACR1DPP4KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |