Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 11/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784459 | 0.85 | TACR1 (0.53) | TACR1BRD4KCNA3NTRK1TDP1 | |
| SCHEMBL27418176 | 0.82 | TACR1 (0.43) | TACR1TDP1RXRADPP4 | |
| SCHEMBL8785610 | 0.79 | TACR1 (0.47) | TACR1BRD4KCNA3NTRK1TDP1 | |
| SCHEMBL8784831 | 0.74 | TACR1 (0.76) | TACR1TDP1 | |
| SCHEMBL8785095 | 0.73 | TACR1 (0.66) | TACR1BRD4KCNA3TDP1 | |
| SCHEMBL12499556 | 0.72 | TACR1 (0.42) | TACR1NTRK1KCNA5KCNH2DPP4 | |
| SCHEMBL12499137 | 0.72 | TACR1 (0.42) | TACR1BRD4NTRK1TDP1DPP4 | |
| SCHEMBL8785661 | 0.72 | TACR1 (0.61) | TACR1 | |
| Hydrochloric Acid SCHEMBL8784883 | 0.71 | TACR1 (0.71) | TACR1 | |
| SCHEMBL12498561 | 0.70 | MEN1 (0.45) | TACR1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |