SCHEMBL12499137

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12499556	0.84	TACR1 (0.42)	TACR1NTRK1LMNAMAPTDPP4
	SCHEMBL12498561	0.81	MEN1 (0.45)	TACR1LMNADPP4HPGDPOLB
	SCHEMBL12499140	0.79	TACR1 (0.44)	TACR1MAPTBRD4HPGDTSHR
	SCHEMBL8948070	0.78	TACR1 (0.51)	TACR1LMNADPP4BRD4POLB
	SCHEMBL15346577	0.76	TACR1 (0.41)	TACR1NTRK1LMNAMAPTDPP4
	SCHEMBL15346580	0.74	TACR1 (0.40)	TACR1NTRK1LMNAMAPTDPP4
	SCHEMBL8784775	0.73	TACR1 (0.55)	TACR1DPP4
	SCHEMBL12498606	0.73	TACR1 (0.52)	TACR1NTRK1POLBTDP1
	SCHEMBL12499588	0.73	TACR1 (0.50)	TACR1LMNAMAPTBRD4HPGD
	SCHEMBL8784647	0.72	TACR1 (0.50)	TACR1NTRK1DPP4BRD4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.