Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241779 | 1.00 | HPGD (0.51) | HPGDRECQLEPHX1MAPTKDM4E | |
| SCHEMBL322172 | 1.00 | HPGD (0.51) | HPGDRECQLEPHX1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL861053 | 0.98 | HPGD (0.50) | HPGDRECQLEPHX1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL14746009 | 0.98 | HPGD (0.50) | HPGDRECQLEPHX1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL2497038 | 0.98 | HPGD (0.50) | HPGDRECQLEPHX1MAPTKDM4E | |
| Acetic Acid SCHEMBL2493436 | 0.95 | HPGD (0.48) | HPGDRECQLEPHX1MAPTKDM4E | |
| Carbamic Acid SCHEMBL30731480 | 0.95 | HPGD (0.48) | HPGDRECQLEPHX1MAPTKDM4E | |
| Trifluoroacetic Acid SCHEMBL27848482 | 0.91 | HPGD (0.44) | HPGDRECQLEPHX1MAPTKDM4E | |
| SCHEMBL181566 | 0.90 | MAPT (0.55) | HPGDRECQLEPHX1MAPTKDM4E | |
| SCHEMBL376485 | 0.90 | MAPT (0.55) | HPGDRECQLEPHX1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3163 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119023611-A | Real-time monitoring method for ketone-amine conversion reaction process and application thereof | 北京衍微科技有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-115974746-B | Synthesis method of tosufloxacin tosylate intermediate | 天地恒一制药股份有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-116354901-A | Thiazolidinedione compound and preparation method and application thereof | 郑州大学 | 2023-06-30 | — | — | CN | claimed |
| CN-111592480-B | Preparation method of cefpiramate intermediate (R) -1-tert-butoxycarbonyl-3-aminopyrrolidine | 山西千岫制药有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-115974746-A | Synthetic method of tosufloxacin tosylate intermediate | 天地恒一制药股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-112094268-B | Compound WEZ series, preparation method thereof and application of compound WEZ series in preparation of medicines | 南京韦尔优众医药有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-112094268-A | Compound WEZ series, preparation method thereof and application of compound WEZ series in preparation of medicines | 南京韦尔优众医药有限公司 | 2020-12-18 | — | — | CN | claimed |
| CN-111592480-A | Preparation method of cefepime intermediate (R) -1-tert-butoxycarbonyl-3-aminopyrrolidine | 山西千岫制药有限公司 | 2020-08-28 | — | — | CN | claimed |
| EP-2623593-B1 | NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE | KANEKA CORP (JP) | 2017-07-12 | — | — | EP | claimed |
| EP-2684953-B1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | KANEKA CORP (JP) | 2017-06-28 | — | — | EP | claimed |
| EP-2202317-A1 | Process for the preparation of optically active chiral amines | Lonza AG (CH) | 2010-06-30 | — | — | EP | claimed |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-06-03 | — | — | US | claimed |
| EP-1987152-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | LONZA AG (CH) | 2010-05-26 | — | — | EP | claimed |
| WO-2010045251-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS, INC. (CA) | 2010-04-22 | — | — | WO | claimed |
| US-20090246837-A1 | Process for The Preparation of Optically Active Chiral Amines | LONZA AG (CH) | 2009-10-01 | — | — | US | claimed |
| CN-101384723-A | Process for the preparation of optically active chiral amines | LONZA AG (CH) | 2009-03-11 | — | — | CN | claimed |
| EP-1987152-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | Lonza AG (CH) | 2008-11-05 | — | — | EP | claimed |
| EP-1897956-A1 | Process for preparation of optically active amines by optical resolution of racemic amines employing a bacterial omega-transaminase | Lonza AG (CH) | 2008-03-12 | — | — | EP | claimed |
| WO-2007093372-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | LONZA AG (CH) | 2007-08-23 | — | — | WO | claimed |
| EP-1818411-A1 | Process for the preparation of optically active chiral amines | Lonza AG (CH) | 2007-08-15 | — | — | EP | claimed |