Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785 | 1.00 | HPGD (0.51) | HPGDRECQLEPHX1MAPTKDM4E | |
| SCHEMBL241779 | 1.00 | HPGD (0.51) | HPGDRECQLEPHX1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL861053 | 0.98 | HPGD (0.50) | HPGDRECQLEPHX1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL14746009 | 0.98 | HPGD (0.50) | HPGDRECQLEPHX1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL2497038 | 0.98 | HPGD (0.50) | HPGDRECQLEPHX1MAPTKDM4E | |
| Acetic Acid SCHEMBL2493436 | 0.95 | HPGD (0.48) | HPGDRECQLEPHX1MAPTKDM4E | |
| Carbamic Acid SCHEMBL30731480 | 0.95 | HPGD (0.48) | HPGDRECQLEPHX1MAPTKDM4E | |
| Trifluoroacetic Acid SCHEMBL27848482 | 0.91 | HPGD (0.44) | HPGDRECQLEPHX1MAPTKDM4E | |
| SCHEMBL181566 | 0.90 | MAPT (0.55) | HPGDRECQLEPHX1MAPTKDM4E | |
| SCHEMBL376485 | 0.90 | MAPT (0.55) | HPGDRECQLEPHX1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1817 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039201-A | Synthesis method of (S) -1-tert-butoxycarbonyl-3-aminopyrrolidine | 苏州汉德创宏生化科技有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-117143083-A | Synthesis method of VEGFR inhibitor Vorolianib | 沈阳药科大学 | 2023-12-01 | — | — | CN | claimed |
| CN-112094268-B | Compound WEZ series, preparation method thereof and application of compound WEZ series in preparation of medicines | 南京韦尔优众医药有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-112094268-A | Compound WEZ series, preparation method thereof and application of compound WEZ series in preparation of medicines | 南京韦尔优众医药有限公司 | 2020-12-18 | — | — | CN | claimed |
| US-7060782-B2 | Process for a two stage melt polymerization for the production of polybenzimidazole having an improved solid state polymerization | PBI PERFORMANCE PRODUCTS, INC. (US) | 2006-06-13 | — | — | US | claimed |
| US-12637426-B2 | 1-cyano-pyrrolidine compounds as USP30 inhibitors | MISSION THERAPEUTICS LIMITED (GB) | 2026-05-26 | — | — | US | disclosed |
| US-12637453-B2 | Pyrazolopyridine inhibitors of c-Jun-n-Terminal kinases and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| CN-122079979-A | Benzofuran derivative and medical application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122080012-A | Thienopyrimidine derivative, preparation method, application and pharmaceutical composition thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122071469-A | PARG inhibitor and preparation method and application thereof | 烟台新药创制山东省实验室 | 2026-05-22 | — | — | CN | disclosed |
| WO-2026106389-A1 | NMT INHIBITOR AND USE THEREOF | 주식회사 이노보테라퓨틱스 | 2026-05-21 | — | — | WO | disclosed |
| EP-4105216-B1 | DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | GENFLEET THERAPEUTICS SHANGHAI INC (CN) | 2026-05-20 | — | — | EP | disclosed |
| EP-1080069-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
| EP-1031563-A1 | SULFONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| WO-1999054284-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-28 | — | — | WO | disclosed |
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637426-B2 | 1-cyano-pyrrolidine compounds as USP30 inhibitors | USP30, USP1, USP10 | HPGD 2931/4885RECQL 691/4885EPHX1 3856/4885 |
| US-12637453-B2 | Pyrazolopyridine inhibitors of c-Jun-n-Terminal kinases and uses thereof | MAP3K1, MAP3K3, MAPK1 | HPGD 1857/4885RECQL 2093/4885EPHX1 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.