Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 7/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803251 | 0.85 | ACHE (0.42) | ACHETSHR | |
| Hydrochloric Acid SCHEMBL785262 | 0.83 | ACHE (0.44) | ACHETSHR | |
| Hydrochloric Acid SCHEMBL785261 | 0.83 | ACHE (0.44) | ACHETSHR | |
| SCHEMBL803162 | 0.79 | ACHE (0.42) | KDM4EACHETSHR | |
| SCHEMBL803167 | 0.78 | ACHE (0.40) | KDM4EACHEAKR1C3AKR1C2 | |
| SCHEMBL877871 | 0.78 | ACHE (0.40) | KDM4EACHEAKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL484838 | 0.78 | ACHE (0.44) | ACHETSHR | |
| Hydrochloric Acid SCHEMBL484839 | 0.78 | ACHE (0.44) | ACHETSHR | |
| Hydrochloric Acid SCHEMBL785346 | 0.77 | ACHE (0.42) | KDM4EACHEAKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL785269 | 0.77 | ACHE (0.42) | KDM4EACHEAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |