Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.72 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | PGR | P06401 | 1/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | PDE4A | P27815 | 1/20 | 0.72 |
| ▸ | BLVRB | P30043 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21156694 | 0.89 | XDH (0.75) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL469542 | 0.88 | XDH (0.57) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL470854 | 0.88 | XDH (0.57) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL2635918 | 0.88 | XDH (0.74) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL31066924 | 0.88 | XDH (0.74) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL470772 | 0.88 | XDH (0.74) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL1357109 | 0.87 | XDH (0.70) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL12133608 | 0.87 | XDH (0.72) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL8867461 | 0.87 | XDH (0.72) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL8867933 | 0.87 | XDH (0.72) | XDHTARBP2ABCC4ABCB11PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012073259-A1 | NOVEL PROCESS FOR THE PREPARATION OF FEBUXOSTAT | INDOCO REMEDIES LIMITED (IN) | 2012-06-07 | — | — | WO | disclosed |
| US-8142999-B2 | HLA alleles associated with adverse drug reactions and methods for detecting such | ACADEMIA SINICA (TW) | 2012-03-27 | — | — | US | disclosed |
| US-20110212439-A1 | HLA ALLELES ASSOCIATED WITH ADVERSE DRUG REACTIONS AND METHODS FOR DETECTING SUCH | ACADEMIA SINICA (TW) | 2011-09-01 | — | — | US | disclosed |