Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267372 | 0.85 | MAPT (0.33) | MAPTGLACA12CA1CA2 | |
| SCHEMBL9272299 | 0.81 | GLA (0.36) | MAPTGLAALDH1A1ABCB1ABCC1 | |
| SCHEMBL8786155 | 0.81 | GLA (0.40) | MAPTGLAALDH1A1ABCB1ABCC1 | |
| SCHEMBL8786389 | 0.80 | GLA (0.37) | MAPTGLAABCB1ABCC1 | |
| SCHEMBL9271281 | 0.76 | KDM4E (0.36) | MAPTALDH1A1KDM4E | |
| SCHEMBL27463748 | 0.75 | ABCB1 (0.45) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL8785937 | 0.75 | ALDH1A1 (0.34) | GLAALDH1A1TDP1 | |
| SCHEMBL8785232 | 0.73 | CA12 (0.37) | MAPTGLACA12CA1CA2 | |
| SCHEMBL8936040 | 0.69 | NPSR1 (0.42) | MAPTGLAALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL8786011 | 0.69 | ABCB1 (0.33) | GLAABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687256-B1 | HYDROXYMETHYL FURAZANE CARBOXYLIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF CARDIO-VASCULAR CONDITIONS | HOECHST AG (DE) | 1997-09-03 | — | — | EP | disclosed |
| EP-0687256-A1 | HYDROXYMETHYL FURAZANE CARBOXYLIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF CARDIO-VASCULAR CONDITIONS | HOECHST AG (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020478-A1 | HYDROXYMETHYL FURAZANE CARBOXYLIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF CARDIO-VASCULAR CONDITIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-15 | — | — | WO | disclosed |