Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12236947 | 0.81 | ABCB1 (0.41) | KMT2AMEN1USP2ABCB1L3MBTL1 | |
| SCHEMBL22992756 | 0.81 | ABCB1 (0.39) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL22992512 | 0.81 | ABCB1 (0.39) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL22992510 | 0.81 | ABCB1 (0.39) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL9348186 | 0.81 | CYP2C9 (0.39) | KMT2AMEN1USP2ABCB1L3MBTL1 | |
| SCHEMBL10655154 | 0.79 | ABCB1 (0.39) | ABCB1L3MBTL1HTTAPEX1 | |
| SCHEMBL10656603 | 0.79 | ABCB1 (0.39) | ABCB1L3MBTL1HTTAPEX1 | |
| SCHEMBL10655166 | 0.79 | ABCB1 (0.39) | ABCB1L3MBTL1HTTAPEX1 | |
| SCHEMBL10655141 | 0.79 | ABCB1 (0.39) | ABCB1L3MBTL1HTTAPEX1 | |
| SCHEMBL10695009 | 0.79 | ABCB1 (0.39) | ABCB1L3MBTL1HTTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761666-A2 | Antidepressant 1-arylalkyl-4-(alkoxypyridinyl)- or 4-(alkoxypyrimidinyl)piperazine derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-03-12 | — | — | EP | disclosed |