Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL7472691 | 0.84 | KMT2A (0.39) | CYP2C9LTB4RLTB4R2KMT2AMEN1 | |
| SCHEMBL8787996 | 0.81 | KMT2A (0.39) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL5542843 | 0.80 | MAOA (0.41) | CYP2C9LTB4RLTB4R2KMT2AMEN1 | |
| SCHEMBL9345601 | 0.75 | CYP2C9 (0.38) | CYP2C9LTB4RLTB4R2KMT2AMEN1 | |
| SCHEMBL8427998 | 0.74 | KMT2A (0.41) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL7422948 | 0.74 | KMT2A (0.41) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL13062858 | 0.71 | ABCB1 (0.57) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL5542835 | 0.70 | ABCB1 (0.41) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL9819039 | 0.69 | HTT (0.40) | KMT2AMEN1USP2MAPT | |
| SCHEMBL9819041 | 0.69 | HTT (0.40) | KMT2AMEN1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |