Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783654 | 0.90 | ABCG2 (0.34) | TSHRNPC1RAB9ASMN1; SMN2ABCG2 | |
| SCHEMBL8783303 | 0.89 | L3MBTL1 (0.39) | NPC1RAB9AABCG2L3MBTL1AAK1 | |
| SCHEMBL8783252 | 0.81 | ABCG2 (0.34) | TSHRNPC1RAB9ASMN1; SMN2ABCG2 | |
| SCHEMBL8783695 | 0.81 | L3MBTL1 (0.39) | NPC1RAB9AABCG2L3MBTL1MGLL | |
| SCHEMBL8783280 | 0.80 | TSHR (0.42) | TSHRNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8783160 | 0.74 | ABCG2 (0.36) | TSHRNPC1RAB9AABCG2L3MBTL1 | |
| SCHEMBL8783269 | 0.74 | MEN1 (0.44) | TSHRSMN1; SMN2ALDH1A1ALOX15MEN1 | |
| SCHEMBL8783143 | 0.73 | ABCG2 (0.35) | NPC1RAB9AABCG2L3MBTL1 | |
| SCHEMBL7346917 | 0.72 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2ABCG2L3MBTL1 | |
| SCHEMBL8783359 | 0.72 | NPSR1 (0.47) | TSHRALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760815-A1 | PROCESSES FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032962-A1 | PROCESSES FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-12-07 | — | — | WO | disclosed |