Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | ECE1 | P42892 | 1/20 | 0.58 |
| ▸ | PRKDC | P78527 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | TNKS | O95271 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.50 |
| ▸ | GABRD | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787057 | 0.79 | MAOB (0.45) | ACEECE1PRKDCMAOBSMN1; SMN2 | |
| SCHEMBL8787918 | 0.76 | ACE (0.51) | ACEECE1PRKDCMAOBTNKS | |
| SCHEMBL31035740 | 0.75 | PRKDC (0.75) | ACEECE1PRKDCSMN1; SMN2HPGD | |
| SCHEMBL30218216 | 0.73 | PRKDC (1.00) | ACEECE1PRKDCSMN1; SMN2CYP3A4 | |
| SCHEMBL3361567 | 0.73 | PRKDC (1.00) | ACEECE1PRKDCSMN1; SMN2CYP3A4 | |
| SCHEMBL9464614 | 0.73 | CYP2A6 (0.42) | MAOBSMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL25246006 | 0.72 | PRKDC (0.71) | ACEECE1PRKDCMAOBSMN1; SMN2 | |
| SCHEMBL5476610 | 0.72 | PRKDC (0.71) | ACEECE1PRKDCSMN1; SMN2HPGD | |
| SCHEMBL7325705 | 0.72 | PRKDC (0.71) | ACEECE1PRKDCMAOBTNKS | |
| SCHEMBL6604961 | 0.71 | ACE (0.50) | ACEECE1PRKDCMAOBTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9110864-A | — | — | None | — | — | JP | disclosed |
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| CN-1148593-A | Production method for chromone derivative and its medicinal composition | KUREHA CHEMICAL IND CO LTD (JP) | 1997-04-30 | — | — | CN | disclosed |
| JP-H09110864-A | CHROMONE DERIVATIVE, ITS PRODUCTION AND MEDICINE COMPOSITION | KUREHA CHEM IND CO LTD | 1997-04-28 | — | — | JP | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |