Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787871 | 0.89 | MAOB (0.78) | MAOBHTTFGFR1ALDH1A1HPGD | |
| SCHEMBL8787171 | 0.88 | MAOB (0.80) | MAOBPRKDCP2RY12 | |
| SCHEMBL8787412 | 0.80 | MAOB (0.54) | MAOBHTTFGFR1MAPK1 | |
| SCHEMBL8788309 | 0.79 | HPGD (0.48) | MAOBHTTFGFR1ALDH1A1HPGD | |
| SCHEMBL8787322 | 0.77 | MAOB (1.00) | MAOBHTTFGFR1ALDH1A1HPGD | |
| SCHEMBL8787862 | 0.75 | MAOB (0.58) | MAOBHTTFGFR1ALDH1A1HPGD | |
| SCHEMBL8787173 | 0.75 | KDM4E (0.60) | MAOBHTTFGFR1ALDH1A1HPGD | |
| SCHEMBL8787257 | 0.75 | MAOB (0.38) | MAOBPRKDCP2RY12 | |
| SCHEMBL8788316 | 0.73 | MAOB (0.67) | MAOBHTTFGFR1HPGDPRKDC | |
| SCHEMBL8787872 | 0.73 | FGFR1 (0.48) | MAOBHTTFGFR1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |