Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788264 | 0.89 | MAOB (0.62) | KDM4EHPGDUSP2CASP1CASP7 | |
| SCHEMBL8788309 | 0.88 | HPGD (0.48) | KDM4EHPGDUSP2CASP1CASP7 | |
| SCHEMBL8787390 | 0.79 | KDM4E (0.63) | KDM4EHPGDUSP2CASP1CASP7 | |
| SCHEMBL8787171 | 0.78 | MAOB (0.80) | MAOBMAOA | |
| SCHEMBL8787953 | 0.77 | MAOB (0.56) | KDM4EHPGDUSP2CASP1CASP7 | |
| SCHEMBL8787466 | 0.76 | MAOB (0.44) | KDM4EHPGDNPSR1MAOBMAPT | |
| SCHEMBL8787414 | 0.75 | ALDH1A1 (0.53) | KDM4EHPGDUSP2CASP1CASP7 | |
| SCHEMBL5310658 | 0.75 | HPGD (1.00) | KDM4EHPGDUSP2CASP1CASP7 | |
| SCHEMBL8788342 | 0.75 | MAOB (0.62) | HPGDMAOBALDH1A1HTTCYP1A2 | |
| SCHEMBL8788341 | 0.74 | MEN1 (0.46) | KDM4EHPGDMAOBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |