Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787502 | 0.85 | FGFR1 (0.47) | KDM4EUSP2HPGDCASP1CASP7 | |
| SCHEMBL8787390 | 0.83 | KDM4E (0.63) | KDM4EUSP2HPGDCASP1CASP7 | |
| SCHEMBL8787953 | 0.82 | MAOB (0.56) | KDM4EUSP2HPGDCASP1CASP7 | |
| SCHEMBL8788309 | 0.79 | HPGD (0.48) | KDM4EUSP2HPGDCASP1CASP7 | |
| SCHEMBL31046136 | 0.76 | FGFR1 (0.51) | KDM4EUSP2HPGDCASP1CASP7 | |
| SCHEMBL31046030 | 0.76 | KDM4E (0.55) | KDM4EUSP2HPGDCASP1CASP7 | |
| SCHEMBL8786828 | 0.75 | KCNMA1 (0.47) | KDM4EHPGDNPSR1HSD17B10HTT | |
| SCHEMBL8787919 | 0.73 | FGFR1 (0.46) | KDM4EUSP2HPGDCASP1CASP7 | |
| SCHEMBL8787226 | 0.72 | HSD17B10 (0.62) | KDM4EUSP2HPGDCASP1CASP7 | |
| SCHEMBL3417306 | 0.71 | HTT (0.73) | HTTPOLBFGFR1ALDH1A1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |