Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 10/20 | 0.59 |
| ▸ | EDNRB | P24530 | 8/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332065 | 0.88 | EDNRA (0.63) | EDNRAEDNRBAGTR1TSHRALDH1A1 | |
| SCHEMBL8906313 | 0.85 | EDNRA (0.64) | EDNRAEDNRBAGTR1TSHRMEN1 | |
| SCHEMBL7341468 | 0.84 | EDNRA (0.58) | EDNRAEDNRBAGTR1TSHRALDH1A1 | |
| SCHEMBL7338422 | 0.80 | EDNRA (0.60) | EDNRAEDNRBAGTR1TSHRALDH1A1 | |
| SCHEMBL7336213 | 0.80 | EDNRA (0.57) | EDNRAEDNRBAGTR1TSHRMEN1 | |
| SCHEMBL8904044 | 0.79 | EDNRA (0.55) | EDNRAEDNRBAGTR1KMT2A | |
| SCHEMBL7339368 | 0.78 | EDNRA (0.61) | EDNRAEDNRBTSHRALDH1A1MEN1 | |
| SCHEMBL7338441 | 0.78 | EDNRA (0.60) | EDNRAEDNRBAGTR1TSHRALDH1A1 | |
| SCHEMBL7336115 | 0.78 | EDNRA (0.61) | EDNRAEDNRBAGTR1MEN1KMT2A | |
| SCHEMBL8903655 | 0.78 | EDNRA (0.61) | EDNRAEDNRBAGTR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774965-A4 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO INC (US) | 1997-10-29 | — | — | EP | disclosed |
| EP-0774965-A1 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO. INC. (US) | 1997-05-28 | — | — | EP | disclosed |