Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097025 | 0.89 | AGTR1 (0.63) | AGTR1AGTR2PPARG | |
| SCHEMBL9043603 | 0.88 | AGTR1 (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL8790049 | 0.85 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9041957 | 0.85 | AGTR1 (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL8788113 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| Water SCHEMBL8790154 | 0.83 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL8790410 | 0.82 | PPARG (0.52) | PPARG | |
| SCHEMBL9042283 | 0.82 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL8788433 | 0.82 | AGTR1 (0.59) | AGTR1AGTR2PPARG | |
| SCHEMBL8789441 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468470-B1 | Benzimidazoles, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0468470-A1 | Benzimidazoles, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |