Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | FADS1 | O60427 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752080 | 0.88 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4GAA | |
| SCHEMBL9277982 | 0.84 | CYP3A4 (0.57) | ALDH1A1TSHRHSD17B10CYP3A4GAA | |
| SCHEMBL8787273 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TSHRHSD17B10CYP3A4GAA | |
| SCHEMBL8786921 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4GAA | |
| SCHEMBL10955418 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4GAA | |
| SCHEMBL27413689 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4GAA | |
| SCHEMBL31190001 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4GAA | |
| SCHEMBL8759548 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4GAA | |
| SCHEMBL4975483 | 0.81 | CYP3A4 (0.57) | ALDH1A1TSHRHSD17B10CYP3A4GAA | |
| SCHEMBL8788598 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518374-B1 | A process for the preparation of alkyl 3-chloroanthranilates | DOWELANCO (US) | 1996-05-01 | — | — | EP | claimed |
| EP-0518374-A2 | A process for the preparation of alkyl 3-chloroanthranilates | DOWELANCO (US) | 1992-12-16 | — | — | EP | claimed |
| US-5118832-A | 1,2-dichloro-5,5-dimethylhydantoin chlorinating agent; selective acetylation of 5-chloro isome r to purify | DOWELANCO (US) | 1992-06-02 | — | — | US | claimed |
| EP-0508682-B1 | Antibiotic carbapenem derivatives | ZENECA LTD (GB) | 1997-07-23 | — | — | EP | disclosed |
| US-5541178-A | THIENAMYCINS | ZENECA LIMITED (GB) | 1996-07-30 | — | — | US | disclosed |
| EP-0518374-B1 | A process for the preparation of alkyl 3-chloroanthranilates | DOWELANCO (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0518374-A2 | A process for the preparation of alkyl 3-chloroanthranilates | DOWELANCO (US) | 1992-12-16 | — | — | EP | disclosed |
| CN-1066657-A | Antimicrobial compounds | ICI PLC (GB) | 1992-12-02 | — | — | CN | disclosed |
| WO-1992017481-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD. (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0508682-A1 | Antibiotic carbapenem derivatives | ZENECA LIMITED (GB) | 1992-10-14 | — | — | EP | disclosed |