Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.34 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22902378 | 0.83 | SLC6A12 (0.43) | PEPDMEN1BLMKMT2AGABRR1 | |
| SCHEMBL11288088 | 0.83 | SLC6A12 (0.43) | PEPDMEN1BLMKMT2AGABRR1 | |
| SCHEMBL6655316 | 0.79 | PEPD (0.38) | PEPDMEN1BLMKMT2A | |
| SCHEMBL8789041 | 0.79 | PEPD (0.42) | PEPDMEN1BLMKMT2AGABRR1 | |
| SCHEMBL30572429 | 0.78 | PEPD (0.45) | PEPDMEN1BLMKMT2AGABRR1 | |
| SCHEMBL11447726 | 0.78 | PEPD (0.37) | PEPDMEN1BLMKMT2A | |
| SCHEMBL9376361 | 0.76 | PEPD (0.42) | PEPDMEN1BLMKMT2AGABRR1 | |
| SCHEMBL11447685 | 0.76 | PEPD (0.42) | PEPDMEN1BLMKMT2AGABRR1 | |
| SCHEMBL13761134 | 0.76 | PEPD (0.42) | PEPDMEN1BLMKMT2AGABRR1 | |
| SCHEMBL7907529 | 0.76 | PEPD (0.42) | PEPDMEN1BLMKMT2AGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468470-B1 | Benzimidazoles, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-04-16 | — | — | EP | claimed |
| EP-0468470-A1 | Benzimidazoles, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-01-29 | — | — | EP | claimed |
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| EP-0468470-B1 | Benzimidazoles, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5587393-A | ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION | DR. KARL THOMAE GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |
| EP-0468470-A1 | Benzimidazoles, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |