Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324919 | 0.84 | ATM (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL135162 | 0.84 | ATM (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL343598 | 0.82 | CA12 (0.58) | TDP1L3MBTL1ALDH1A1MAPTRECQL | |
| SCHEMBL134300 | 0.81 | ATM (0.95) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL134024 | 0.81 | ATM (0.95) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL8789789 | 0.79 | ALDH1A1 (0.70) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| Benzophenone SCHEMBL29105776 | 0.79 | ALDH1A1 (0.78) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| Benzophenone SCHEMBL28127869 | 0.78 | ALDH1A1 (0.88) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| Benzophenone SCHEMBL6061130 | 0.78 | ALDH1A1 (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| Benzophenone SCHEMBL28491203 | 0.78 | ALDH1A1 (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-B1 | New benzene derivatives having (NGF) production-promoting activity | SANKYO CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |