Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789831 | 0.94 | PPARG (0.48) | PPARG | |
| SCHEMBL8789802 | 0.92 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL7302939 | 0.88 | AGTR1 (0.43) | AGTR1AGTR2PPARG | |
| SCHEMBL9097368 | 0.83 | PPARG (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL7300056 | 0.82 | AGTR1 (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL8790413 | 0.81 | AGTR1 (0.46) | AGTR1AGTR2PPARG | |
| SCHEMBL7301596 | 0.81 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9095911 | 0.81 | PPARG (0.51) | PPARG | |
| SCHEMBL8788943 | 0.81 | PPARG (0.46) | PPARG | |
| SCHEMBL8790156 | 0.81 | PPARG (0.47) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468470-B1 | Benzimidazoles, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5587393-A | ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION | DR. KARL THOMAE GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |
| EP-0468470-A1 | Benzimidazoles, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |