Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14654212 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9ANPC1USP2HSD17B10 | |
| SCHEMBL6037481 | 0.80 | L3MBTL1 (0.59) | SMN1; SMN2RAB9ANPC1HSD17B10L3MBTL1 | |
| SCHEMBL13340599 | 0.78 | GLA (0.58) | SMN1; SMN2RAB9ANPC1USP2HSD17B10 | |
| SCHEMBL13923442 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9ANPC1USP2HSD17B10 | |
| SCHEMBL295077 | 0.78 | L3MBTL1 (0.55) | SMN1; SMN2RAB9ANPC1USP2HSD17B10 | |
| SCHEMBL9415751 | 0.77 | GLA (0.67) | SMN1; SMN2RAB9ANPC1USP2HSD17B10 | |
| SCHEMBL11195842 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1USP2HSD17B10 | |
| SCHEMBL3404224 | 0.75 | L3MBTL1 (0.63) | SMN1; SMN2RAB9ANPC1USP2HSD17B10 | |
| SCHEMBL7694058 | 0.75 | GLA (0.65) | SMN1; SMN2RAB9ANPC1USP2HSD17B10 | |
| SCHEMBL5778349 | 0.75 | L3MBTL1 (0.57) | SMN1; SMN2RAB9ANPC1USP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | disclosed |