Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905541 | 0.81 | HTR1A (0.56) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL23328083 | 0.80 | TSHR (0.42) | BTN3A1TSHRPKM | |
| SCHEMBL2751224 | 0.79 | TSHR (0.41) | BTN3A1TSHRSRC | |
| SCHEMBL2750626 | 0.78 | BTN3A1 (0.35) | BTN3A1HTR1ATSHRSRCL3MBTL1 | |
| SCHEMBL8792286 | 0.78 | TSHR (0.41) | BTN3A1TSHR | |
| SCHEMBL26985746 | 0.78 | TSHR (0.41) | BTN3A1TSHR | |
| SCHEMBL8792111 | 0.76 | TSHR (0.47) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8790985 | 0.75 | BTN3A1 (0.33) | BTN3A1TSHR | |
| SCHEMBL29868024 | 0.75 | BTN3A1 (0.33) | BTN3A1TSHR | |
| SCHEMBL8790350 | 0.74 | BTN3A1 (0.36) | BTN3A1TSHRSRCRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558959-B1 | Phosphonooxy and carbonate derivatives of taxol | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0558959-A1 | Phosphonooxy and carbonate derivatives of taxol | Bristol-Myers Squibb Company (US) | 1993-09-08 | — | — | EP | disclosed |