SCHEMBL8790673

SCHEMBL8790673

[CH2]c1cccc(CCCCF)c1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.42
TAAR1 Q96RJ0 6/20 0.38
MGLL Q99685 1/20 0.37
IGF1R P08069 1/20 0.36
ALOX15 P16050 1/20 0.36
LPL P06858 2/20 0.36
LIPG Q9Y5X9 2/20 0.36
DRD2 P14416 2/20 0.34
DRD1 P21728 1/20 0.34
HRH1 P35367 2/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9200094 0.94 TAAR1 (0.39) MAOATAAR1MGLLLPLLIPG
SCHEMBL1533528 0.85 TAAR1 (0.42) MAOATAAR1DRD2DRD1SLC6A3
SCHEMBL10903519 0.80 CYP4F2 (0.50) MAOAMGLLIGF1RALOX15LPL
SCHEMBL5252629 0.80 LPL (0.56) LPLLIPG
SCHEMBL7337578 0.78 LPL (0.57) LPLLIPGSLC6A4SLC6A3
SCHEMBL7332490 0.78 LPL (0.57) LPLLIPGSLC6A4SLC6A3
SCHEMBL9063297 0.78 LPL (0.57) LPLLIPGSLC6A4SLC6A3
SCHEMBL10903699 0.78 CYP4F2 (0.49) MGLLIGF1RALOX15LPLLIPG
SCHEMBL9064256 0.78 LPL (0.57) LPLLIPGSLC6A4SLC6A3
SCHEMBL11650281 0.78 LPL (0.57) LPLLIPGSLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639776-A CROP PESTICIDE; NONPHYTOTOXIC, KIDNEY BEANS, ORANGES OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-06-17 US disclosed
EP-0751130-A1 4,5-DIHYDROPYRAZOLE-5-THIONE DERIVATIVES AND ACARICIDE CONTAINING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-01-02 EP disclosed