Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 8/20 | 0.40 |
| ▸ | ACE | P12821 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791310 | 0.84 | MAPT (0.50) | MAPTGAASMYD3MTNR1AMME | |
| SCHEMBL17675115 | 0.83 | MAPT (0.65) | MAPTGAASMYD3MTNR1AMME | |
| SCHEMBL32680077 | 0.81 | MAPT (0.50) | MAPTGAASMYD3MTNR1AMME | |
| SCHEMBL8067762 | 0.81 | MAPT (0.50) | MAPTGAASMYD3MTNR1AMME | |
| SCHEMBL4734530 | 0.77 | SMYD3 (0.56) | MAPTGAASMYD3MTNR1AHTR1A | |
| SCHEMBL1545216 | 0.77 | SMYD3 (0.52) | MAPTGAASMYD3MTNR1AHTR1A | |
| SCHEMBL4730904 | 0.77 | SMYD3 (0.52) | MAPTGAASMYD3MTNR1AHTR1A | |
| SCHEMBL8401235 | 0.75 | MAPT (0.48) | MAPTGAASMYD3MTNR1AMME | |
| SCHEMBL17647218 | 0.74 | MAPT (0.47) | MAPTGAASMYD3MTNR1AMME | |
| SCHEMBL4019694 | 0.74 | SMYD3 (0.58) | MAPTGAASMYD3MTNR1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560235-B1 | Condensed heterocyclic ketone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5462934-A | Cholinesterase inhibitor; learning enhancement | TAKEDA CHEMICAL INDUSTRIES (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0560235-A1 | Condensed heterocyclic ketone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-09-15 | — | — | EP | disclosed |