SCHEMBL32680077

SCHEMBL32680077

NC(=O)C1CCCc2ccccc2N1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.50
SMYD3 Q9H7B4 1/20 0.50
GAA P10253 1/20 0.50
MTNR1A P48039 3/20 0.44
MASP2 O00187 1/20 0.39
F2 P00734 1/20 0.39
MME P08473 6/20 0.39
PTK2B Q14289 1/20 0.38
ACE P12821 2/20 0.38
SIRT2 Q8IXJ6 1/20 0.38
SIRT1 Q96EB6 1/20 0.38
HTR1A P08908 2/20 0.37
HTR2A P28223 2/20 0.37
DRD3 P35462 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8067762 1.00 MAPT (0.50) MAPTSMYD3GAAMTNR1AMASP2
SCHEMBL1268909 0.90 SMYD3 (0.59) MAPTSMYD3GAAMTNR1AMASP2
SCHEMBL17675115 0.85 MAPT (0.65) MAPTSMYD3GAAMTNR1AMME
SCHEMBL8791310 0.84 MAPT (0.50) MAPTSMYD3GAAMTNR1AMME
SCHEMBL8790874 0.81 MAPT (0.47) MAPTSMYD3GAAMTNR1AF2
SCHEMBL25937486 0.80 SMYD3 (0.53) MAPTSMYD3GAAMTNR1AMASP2
SCHEMBL2266601 0.80 GAA (0.71) MAPTSMYD3GAAMTNR1AMASP2
SCHEMBL10742930 0.80 GAA (0.71) MAPTSMYD3GAAMTNR1AMASP2
SCHEMBL30900484 0.80 GAA (0.71) MAPTSMYD3GAAMTNR1AMASP2
Hydrochloric Acid SCHEMBL28262901 0.78 GAA (0.69) MAPTSMYD3GAAMTNR1AMASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564547-B2 Compositions, formulations, and methods for skin treatment ODDITY LABS, LLC (US) 2026-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564547-B2 Compositions, formulations, and methods for skin treatment MCOLN1, H1-0, APOL1 MAPT 3212/4885SMYD3 1469/4885GAA 4201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.