Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ACP3 | P15309 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27525245 | 0.87 | MEN1 (0.61) | MEN1HPGDKMT2AL3MBTL1CYP3A4 | |
| SCHEMBL3474640 | 0.87 | MEN1 (0.61) | MEN1HPGDKMT2AL3MBTL1CYP3A4 | |
| SCHEMBL31580477 | 0.87 | MEN1 (0.61) | MEN1HPGDKMT2AL3MBTL1CYP3A4 | |
| SCHEMBL2545597 | 0.87 | MEN1 (0.61) | MEN1HPGDKMT2AL3MBTL1CYP3A4 | |
| SCHEMBL6302886 | 0.87 | MEN1 (0.61) | MEN1HPGDKMT2AL3MBTL1CYP3A4 | |
| SCHEMBL2150915 | 0.84 | MEN1 (0.52) | MEN1HPGDKMT2AL3MBTL1CYP3A4 | |
| SCHEMBL19354525 | 0.84 | TSHR (0.57) | MEN1HPGDKMT2AL3MBTL1CYP3A4 | |
| SCHEMBL254876 | 0.83 | TSHR (0.61) | MEN1HPGDKMT2AL3MBTL1TSHR | |
| SCHEMBL2023789 | 0.83 | TSHR (0.61) | MEN1HPGDKMT2AL3MBTL1TSHR | |
| SCHEMBL9211692 | 0.82 | L3MBTL1 (0.53) | MEN1HPGDKMT2AL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562480-B1 | 1-phenyl-5-substituted-1H-1, 2,4-triazole-3-carboxamide derivates, process for preparation of the same, and fungicidal composition comprising the same | KUREHA CHEMICAL IND CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0552558-B1 | 1,5-Diphenyl-1H-1,2,4-triazole-3-carboxamide derivatives, process for preparation of the same, antifungal composition comprising the same | KUREHA CHEMICAL IND CO LTD (JP) | 1996-05-22 | — | — | EP | disclosed |
| EP-0562480-A1 | 1-phenyl-5-substituted-1H-1, 2,4-triazole-3-carboxamide derivates, process for preparation of the same, and fungicidal composition comprising the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0562479-A1 | 1-Phenyl-5-heterocyclic-1H-1, 2,4-triazole-3-carboxamide derivates, process for preparation of the same, and fungicidal composition comprising the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0552558-A1 | 1,5-Diphenyl-1H-1,2,4-triazole-3-carboxamide derivatives, process for preparation of the same, antifungal composition comprising the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0371564-A2 | (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-06-06 | — | — | EP | disclosed |