Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.55 |
| ▸ | FNTB | P49356 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088137 | 0.82 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL28351050 | 0.82 | MAPT (0.64) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL29629485 | 0.81 | MEN1 (0.68) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL468399 | 0.81 | MEN1 (0.68) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL9531242 | 0.81 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL15577112 | 0.78 | MEN1 (0.50) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL4628084 | 0.78 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL29407882 | 0.78 | MAPT (0.72) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL21479833 | 0.78 | MAPT (0.72) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL4856078 | 0.76 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764163-A1 | TACHYKININ (NK 1) RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995033744-A1 | TACHYKININ (NK1) RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-12-14 | — | — | WO | disclosed |