Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107230 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL22216666 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL60131 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL1828721 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL728754 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL24782761 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL21422636 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL21057384 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL21057351 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 | |
| SCHEMBL11147768 | 1.00 | HTR6 (0.54) | HTR6PHGDHMGLLL3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724827-A | Fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-03-03 | — | — | CN | disclosed |
| WO-2021063373-A1 | TRPV1 AGONIST AND PREPARATION METHOD THEREFOR AND USE THEREOF | 南京清普生物科技有限公司 | 2021-04-08 | — | — | WO | disclosed |
| EP-3562822-B1 | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS | MITOBRIDGE INC (US) | 2021-03-10 | — | — | EP | disclosed |
| CN-101242846-A | Synergistic modulation of FLT3 kinase using thienopyrimidine and thienopyridine kinase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |
| CN-101242845-A | Synergistic modulation of FLT3 kinase using a farnesyl transferase inhibitor | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |
| CN-101242847-A | Synergistic modulation of FLT3 kinase using aminopyrimidines kinase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |