Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721470 | 0.82 | KCNH2 (0.62) | KCNH2TSHRHTTRECQLALDH1A1 | |
| SCHEMBL442779 | 0.80 | MCL1 (0.60) | KCNH2TSHRHTTRECQLALDH1A1 | |
| SCHEMBL114250 | 0.80 | KMT2A (0.60) | KCNH2TSHRHTTRECQLALDH1A1 | |
| SCHEMBL23665644 | 0.80 | POLB (0.50) | KCNH2ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL7030842 | 0.79 | KCNH2 (0.68) | KCNH2TSHRHTTRECQLALDH1A1 | |
| SCHEMBL720361 | 0.79 | POLB (0.49) | KCNH2TSHRHTTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9789912 | 0.79 | MCL1 (0.58) | KCNH2TSHRHTTRECQLALDH1A1 | |
| SCHEMBL992866 | 0.79 | KCNH2 (0.58) | KCNH2TSHRHTTRECQLALDH1A1 | |
| SCHEMBL25472764 | 0.79 | KCNH2 (0.58) | KCNH2TSHRHTTRECQLALDH1A1 | |
| SCHEMBL353910 | 0.79 | KCNH2 (0.58) | KCNH2TSHRHTTRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682537-B1 | MODULATORS OF CELLULAR ADHESION | SARCODE BIOSCIENCE INC (US) | 2012-03-28 | — | — | EP | disclosed |